A 21-year-old woman come to emergency room,she states that for past 2 days she experienced muscle ache, insomnia,diarrhea,sweating and depression mood. The patient have been used heroin 2 years, which of the following treatment is best

• A、benzodiazepine
• B、antipsychotic
• C、antidepressant drug
• D、methadone
• E、clinical observation